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Antigenic Specificity | Human SIRT1 / Sirtuin 1 |
Clone | [7B7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The SIRT family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes including transcriptional regulation, cell cycle progression, DNA damage repair and aging. Sirtuins utilize NAD+ as a substrate to catalyze deacetylation of specific acetylated protein and histones. SIRT1 has been shown to be induced by caloric restriction (CR) in several tissues and SIRT1 mediated deacetylase activity attenuates B-amyloid content in the brain during CR. |
Immunogen | Immunogen Description: SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Other Names | [SIRT1 / Sirtuin 1 (clone 7B7) IHC-plus; SIRT1; SIR2-like protein 1; SIR2alpha; SIR2L1; Sirtuin 1; Sir2-like 1; Sirtuin type 1; HSIR2; HSIRT1; Human SIRT1; Sirtuin 1], [SIRT1; SIRT1; SIR2L1; SIR2L1; hSIRT1; hSIR2; 75SirT1] |
Gene, Accession # | [SIRT1], Gene ID: 23411, NCBI: NP_036370.2, UniProt: Q96EB6 |
Catalog # | MBS245888 |
Price | $605 |
Order / More Info | Human SIRT1 / Sirtuin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |