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Antigenic Specificity | Gelsolin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Gelsolin(GSN) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat. Background: Gelsolin also known as GNS is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily. The gene was assigned to human chromosome 9q33.2. Gelsolin is also known as brevin, or actin-depolymerizing factor; it is the principal intracellular and extracellular actin-severing protein. Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis. Gelso |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Gelsolin (763-775aa WDDDYWSVDPLDR), identical to the related rat sequence, and different from the related mouse sequence by one amino acid. |
Other Names | [Gelsolin; gelsolin; Actin depolymerizing factor; Actin-depolymerizing factor; ADF; AGEL; Amyloidosis Finnish type; Brevin; DKFZp313L0718; GELS_HUMAN; Gelsolin; GSN], [GSN; GSN; ADF; AGEL; ADF] |
Gene, Accession # | [GSN], Gene ID: 2934, NCBI: P06396.1, UniProt: P06396 |
Catalog # | MBS176929 |
Price | $315 |
Order / More Info | Gelsolin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |