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Antigenic Specificity | Integrin beta7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of Integrin beta7. ITGB7 encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript vari |
Immunogen | Immunogen: Synthesized peptide derived from part region of human Integrin beta7 protein at amino acid sequence of 671-720 |
Other Names | [Rabbit Integrin beta7; Integrin beta-7; Gut homing receptor beta subunit] |
Gene, Accession # | Gene ID: 3695, NCBI: NP_000880.1, UniProt: P26010 |
Catalog # | MBS9709522 |
Price | $130, $220, $325 |
Order / More Info | Integrin beta7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |