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Antigenic Specificity | caspase-4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq] |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 68 and 132 of caspase-4 |
Other Names | [caspase-4 isoform alpha; Caspase-4; caspase-4; caspase 4, apoptosis-related cysteine peptidase; ICE(rel)-II; Protease ICH-2; Protease TX] |
Gene, Accession # | Gene ID: 837, NCBI: NP_001216 |
Catalog # | MBS9406507 |
Price | $320 |
Order / More Info | caspase-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |