MSH2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMSH2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: Western blot analysis of extracts of various cell lines, using MSH2 antibody. Immunofluorescence analysis of HeLa cell using MSH2 antibody. Blue: DAPI for nuclear staining. The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between non-identical DNA sequences and induces both checkpoint and apoptotic responses following certain types of DNA damage (1). MSH2 (MutS homologue 2) forms the hMutS-+/- dimer with MSH6 and is an essential component of the mismatch repair process. hMutS-+/- is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins and the Rad50-Mre11-NBS1 complex (2).Mutations in MSH2 have been found in a large pr
ImmunogenImmunogen: Recombinant protein of human MSH2
Other Names[MSH2; MSH2; MSH2], [MSH2]
Gene, Accession #[MSH2], NCBI: APC94174.1
Catalog #MBS419547
Price$385
Order / More InfoMSH2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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