Human CD257 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human CD257 |
| Clone | [2B] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | IgG concentration 1.0mg/ml after reconstitution. |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item specifically recognises CD257 (otherwise known as BAFF/BLyS), a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus.. . CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.This antibody has not been cross-adsorbed and may react with homologous proteins from related species. MBS212959 specifically recognises CD2 |
| Immunogen | Immunogen: Recombinant full-length mature human CD257 expressed in E Coli. Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [tumor necrosis factor ligand superfamily member 13B isoform 2; Tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor ligand superfamily member 13B; ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor-like protein ZTNF4; tumor necrosis factor (ligand) superfamily, member 13b; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD_antigen: CD257Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form], [TNFSF13B; TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1] |
| Gene, Accession # | [CD257], Gene ID: 10673, NCBI: NP_001139117.1, UniProt: Q9Y275 |
| Catalog # | MBS212959 |
| Price | $515 |
| Order / More Info | Human CD257 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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