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Antigenic Specificity | Cdc37 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Hsp90 co-chaperone Cdc37(CDC37) detection. Tested with WB in Human. Background: Hsp90 co-chaperone Cdc37, also called P50CDC37 is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This gene is mapped to 19p13.2. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is though to play a critical role in directing Hsp90 to its target kinases. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc37 (361-376aa DPLLEAVPKTGDEKDV), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids. |
Other Names | [Hsp90 co-chaperone Cdc37; cell division cycle 37; CDC 37; CDC37; CDC37 cell division cycle 37 homolog; CDC37 cell division cycle 37 S cerevisiae homolog; Cdc37 homolog; CDC37 protein; CDC37_HUMAN; CDC37A; Cell division cycle 37 homolog; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co chaperone Cdc37; Hsp90 co-chaperone Cdc37; p50; p50Cdc37; S cerevisiae hypothetical protein CDC37; S. cerevisiae hypothetical protein CDC37], [CDC37; CDC37; P50CDC37; CDC37A] |
Gene, Accession # | [CDC37], Gene ID: 11140, NCBI: Q16543.1, UniProt: Q16543 |
Catalog # | MBS176315 |
Price | $280 |
Order / More Info | Cdc37 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |