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Antigenic Specificity | HDAC5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for |
Immunogen | Immunogen: A synthetic peptide of human HDAC5 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Other Names | [HD5; NY-CO-9] |
Gene, Accession # | [HDAC5], Gene ID: 10014, NCBI: NP_001015053.1 |
Catalog # | MBS2536144 |
Price | $150, $225, $360 |
Order / More Info | HDAC5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |