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Antigenic Specificity | Amyloid Beta 1-16 (Abeta1-16) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot (IB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes Abeta1-16 as well as other Abeta peptides: Abeta37, Abeta38, Abeta39, Abeta40, and Abeta42. NOTE: When administered to young Tg2576 mice with minimal Abeta deposition and to older mice with higher Abeta loads, this antibody reduced Abeta accumulation in the brain. Accumulation and aggregation of amyloid beta (Abeta) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Abeta is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Abeta. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the |
Immunogen | Antigen: Synthetic peptide corresponding to Abeta1-16. |
Other Names | n/a |
Gene, Accession # | [Abeta1-16] |
Catalog # | MBS190935 |
Price | $395 |
Order / More Info | Amyloid Beta 1-16 (Abeta1-16) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |