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Antigenic Specificity | Phospho-ALK-Y1096 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (c |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y1096 of human ALK Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CD246; NBLST3] |
Gene, Accession # | [ALK-Y1096], Gene ID: 238, NCBI: NP_004295.2, UniProt: Q9UM73 |
Catalog # | MBS8537001 |
Price | $300 |
Order / More Info | Phospho-ALK-Y1096 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |