PLA2G6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PLA2G6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PLA2G6 antibody detects endogenous levels of total PLA2G6. Function: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.Subunit Structure: Forms large oligomeric 270-350 kDa structures. |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm and Membrane. Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes. Tissue Specificity: Four different transcripts were found to be expressed in a distinct tissue distribution. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (93%), Xenopus (86%) |
| Other Names | [85 kDa calcium independent phospholipase A2; 85/88 kDa calcium-independent phospholipase A2; BB112799; CaI PLA2; CaI-PLA2; CaIPLA2; Calcium independent phospholipase A2; CTA-228A.2; Cytosolic calcium independent phospholipase A2; EC 3.1.1.4; Group VI phospholipase A2; Group VI, A; GVI; GVI PLA2; INAD1; Intracellular membrane associated calcium independent phospholipase A2 beta; Intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA(2)beta; iPLA2 beta; iPLA2-beta; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; Neurodegeneration with brain iron accumulation 2; OTTHUMP00000199457; PARK14; Patatin like phospholipase domain containing 9; Patatin like phospholipase domain containing protein 9; Patatin-like phospholipase domain-containing protein 9; Phospholipase A2 calcium independent; Phospholipase A2 calcium independent group VI A; Phospholipase A2 group VI; Phospholipase A2 group VI cytosolic calcium independent; Phospholipase A2, group VI (cytosolic, calcium independent); PLA2; PLA2G6; PLPL9_HUMAN; PNPLA9] |
| Gene, Accession # | [PLA2G6], Gene ID: 8398, NCBI: NP_001004426.1, UniProt: O60733 |
| Catalog # | MBS9606174 |
| Price | $240, $280 |
| Order / More Info | PLA2G6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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