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Antigenic Specificity | HLA-B, 62-90 |
Clone | [528CT10.4.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HLA-B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from human HLA-B. HLA-B belongs to the HLA class I heavy chain paralogues.This class I molecule is a heterodimer consisting of a heavy chainand a light chain (beta-2 microglobulin). The heavy chain isanchored in the membrane. Class I molecules play a central role inthe immune system by presenting peptides derived from theendoplasmic reticulum lumen. They are expressed in nearly allcells. The heavy chain is approximately 45 kDa and its genecontains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3encode the alpha1 and alpha2 domains, which both bind the peptide,exon 4 encodes the al |
Immunogen | n/a |
Other Names | [HLA class I histocompatibility antigen; B-27 alpha chain; MHC class I antigen B*27; HLA-B; HLAB] |
Gene, Accession # | [HLA-B], Gene ID: 34305677, NCBI: P03989.2, UniProt: P03989 |
Catalog # | MBS9200593 |
Price | $165, $370 |
Order / More Info | HLA-B, 62-90 Antibody from MYBIOSOURCE INC. |
Product Specific References | Parsons, M.S., et al. J. Infect. Dis. 202 SUPPL 3, S356-S360 (2010) : Brockman, M.A., et al. J. Virol. 84(22):11937-11949(2010) Noble, J.A., et al. Diabetes 59(11):2972-2979(2010) Lipponen, K., et al. Diabetes (2010) In press : Liao, Y.Q., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 18(4):1055-1058(2010) |