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Antigenic Specificity | DAP Kinase 3 (IN), (Death-associated protein kinase 3 (Internal Epitope) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase1. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic act |
Immunogen | Immunogen: Antibody raised against a synthetic protein corresponding to amino acids 279 to 298 of the human ZIP kinase protein. |
Other Names | [ZIP kinase; Internal; DAPK3], [DAPK3; DAPK3; ZIP; ZIPK; ZIPK; DAP kinase 3; Dlk; ZIP-kinase] |
Gene, Accession # | Gene ID: 1613, NCBI: NP_001339.1, UniProt: O43293 |
Catalog # | MBS395661 |
Price | $510 |
Order / More Info | DAP Kinase 3 (IN), (Death-associated protein kinase 3 (Internal Epitope) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |