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Antigenic Specificity | PITRM1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PITRM1 |
Other Names | [presequence protease, mitochondrial isoform 1; Presequence protease, mitochondrial; presequence protease, mitochondrial; pitrilysin metallopeptidase 1; Pitrilysin metalloproteinase 1; Metalloprotease 1; hMP1] |
Gene, Accession # | [PITRM1], Gene ID: 10531, NCBI: NP_001229236.1, UniProt: Q5JRX3 |
Catalog # | MBS3222184 |
Price | $335 |
Order / More Info | PITRM1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |