CD33 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD33
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: At least three isoforms of CD33 are known to exist; this antibody will detect all three isoforms. CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the center of human CD33.
Other Names[Myeloid surface antigen CD33, p67, SIGLEC3]
Gene, Accession #[CD33], Gene ID: 945, NCBI: NP_001763
Catalog #MBS9405044
Price$320
Order / More InfoCD33 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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