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Antigenic Specificity | HDAC7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HDAC7 protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors By similarity. May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human HDAC7. |
Other Names | [histone deacetylase 7A] |
Gene, Accession # | [HDAC7], Gene ID: 51564, NCBI: NP_001091886.1, UniProt: Q8WUI4 |
Catalog # | MBS9413363 |
Price | $200, $255 |
Order / More Info | HDAC7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |