Caspase-8 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Caspase-8 |
| Clone | [ABM14C1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as other autoimmune diseases. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase-8 involves a two-step proteolysis: the cleavage of caspase-8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.The Active/Cleaved Caspase-8 polyclonal antisera recognizes the large and small subunits of active/cleaved caspase-8. Whereas the antisera |
| Immunogen | Antigen: Caspase-8. Immunogen Information: A partial length recombinant protein (a.a 179-385) of Caspase-8 was used as the immunogen for this antibody. Conjugation: Unconjugated |
| Other Names | [Apoptotic cysteine protease; Apoptotic protease Mch-5; FADD-homologous ICE/ced-3-like protease; CE-like apoptotic protease 5], [CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; MCH5; CASP-8; FLICE; MACH] |
| Gene, Accession # | [CASP8], Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790 |
| Catalog # | MBS668940 |
| Price | $290 |
| Order / More Info | Caspase-8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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