NHERF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNHERF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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DescriptionRabbit polyclonal to Human NHERF1. Na+/H+ exchanger regulatory factor (NHERF1 or EBP-50) is one of several related PDZ domain-containing proteins (1). NHERF1 was first identified as a necessary cofactor for cyclic AMP-associated inhibition of Na+/ H+ exchanger isoform 3 (NHE3) (2). NHERF1 is a multifunctional adaptor protein that interacts with receptors and ion transporters via its PDZ domains, and with the ERM family of proteins, including merlin, via its carboxy-terminus (2,3). NHERF1 may play an important role in breast cancer. Estrogen has been found to induce NHERF1 in estrogen receptor-positive breast cancer cells (2,3). Furthermore, NHERF1 has been shown to bind to PDGFR, which is activated in breast carcinomas. NHERF1 has been foun
ImmunogenImmunogen: A Fusion protein of human NHERF1
Other Names[SLC9A3R1; NHERF1; NHERF1; NHERF, NHERF1], [SLC9A3R1; SLC9A3R1; EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2; NHERF; NHERF1; NHERF-1; EBP50]
Gene, Accession #Gene ID: 9368, NCBI: NP_004243.1, UniProt: O14745
Catalog #MBS125205
Price$200, $275, $430
Order / More InfoNHERF1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Donowitz, M. et al. (2005) J Physiol 567, 3-11. 2. Voltz, J.W. et al. (2001) Oncogene 20, 6309-14. 3. Stemmer-Rachamimov, A.O. et al. (2001) Am J Pathol 158, 57-62. 4. Takahashi, Y. et al. (2006) EMBO J 25, 910-20. 5. Wheeler, D. et al. (2007) J Biol Chem 282, 25076-87. 6. Weinman, E.J. et al. (2000) Am J Physiol Renal Physiol 279, F393-9.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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