JAM-C, Mouse Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityJAM-C, Mouse
Clone19H36
Host SpeciesRat
Reactive Speciesreactivity: mouse. cross reactivity: human
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsF, Flow Cytometry (FC/FACS), Immunoassay (IA), Immunoprecipitation (IP)
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DescriptionProduct Description: Junctional adhesion molecule-C (JAM-C) also known as JAM-2 is a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high
Immunogenn/a
Other Names[junctional adhesion molecule C isoform 2; Junctional adhesion molecule C; junctional adhesion molecule C; junctional adhesion molecule 3; JAM-2; Junctional adhesion molecule 3; JAM-3], [JAM3; JAM3; JAMC; JAM-2; JAM-3; JAM-C; UNQ859/PRO1868; JAM-C; JAM-3]
Gene, Accession #[JAM-C], Gene ID: 83700, NCBI: NP_001192258.1
Catalog #MBS584135
Price$520
Order / More InfoJAM-C, Mouse Antibody from MYBIOSOURCE INC.
Product Specific References1. Aurrand-Lions, M et al; JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J Biol Chem 2001, 276: 2733 2. Johnson-Leger, C et al; Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. Blood 2002, 100: 2479
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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