STAT3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | STAT3 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Signal transducer and activator of transcription 3 (STAT3) detection. Tested with WB in Human;Mouse;Rat. Background: The transcription factor, signal transducer and activator of transcription-3 (STAT-3) is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. The mouse STAT3 gene contains 24 exons and spans 30 kb. The translation initiation codon is in exon 2, and the stop codon is in exon 24. STAT3 is mapped to 17q21. It contributes to various physiological processes. Hepatic STAT-3 signaling is thus essential for normal glucose homeostasis and may provide new therapeut |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human STAT3 (139-167aa EKQQMLEQHLQDVRKRVQDLEQKMKVVEN), identical to the related mouse and rat sequences. Ig Type: Rabbit IgG |
| Other Names | [Signal transducer and activator of transcription 3; 1110034C02Rik; Acute Phase Response Factor; Acute-phase response factor; APRF; AW109958; DNA binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; Signal Transductor and Activator of Transcription 3; STAT 3; Stat3; STAT3_HUMAN; signal transducer and activator of transcription 3 (acute-phase response factor)], [STAT3; STAT3; APRF; HIES; ADMIO] |
| Gene, Accession # | [STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763 |
| Catalog # | MBS178221 |
| Price | $280 |
| Order / More Info | STAT3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bhattacharya, S.; Schindler, C. : Regulation of Stat3 nuclear export. J. Clin. Invest. 111: 553-559, 2003. 2. Inoue, H.; Ogawa, W.; Ozaki, M.; Haga, S.; Matsumoto, M.; Furukawa, K.; Hashimoto, N.; Kido, Y.; Mori, T.; Sakaue, H.; Teshigawara, K.; Jin, S.; Iguchi, H.; Hiramatsu, R.; LeRoith, D.; Takeda, K.; Akira, S.; Kasuga, M. : Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nature Med. 10: 168-174, 2004. 3. Miyoshi, K.; Cui, Y.; Riedlinger, G.; Robinson, P.; Lehoczky, J.; Zon, L.; Oka, T.; Dewar, K.; Hennighausen, L. : Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse. Genomics 71: 150-155, 2001. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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