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Antigenic Specificity | Phospho-PKCB1 (Thr642+644) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, sheep, rabbit |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PKCB1(Thr642+644) Antibody detects endogenous levels of PKCB1 only when phosphorylated at Thr642+644. Description: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/C |
Immunogen | Immunogen: A synthesized peptide derived from human PKCB1 around the phosphorylation site of Thr642 644. |
Other Names | [KPCB_HUMAN; PKC beta; PKC-B; PKC-beta; PKCB; Prkcb; PRKCB I; PRKCB II; PRKCB1; PRKCB2; Protein kinase C beta 1; Protein kinase C beta 2; Protein kinase C beta; Protein kinase C beta type; protein kinase C, beta 1 polypeptide] |
Gene, Accession # | [PKCB1], Gene ID: 5579, NCBI: NP_002729.2, UniProt: P05771 |
Catalog # | MBS9610553 |
Price | $225, $280, $340 |
Order / More Info | Phospho-PKCB1 (Thr642+644) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |