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Antigenic Specificity | Human Parathyroid hormone-related protein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expres |
Immunogen | Immunogen: Recombinant human Parathyroid hormone-related protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9680 / sc-20728 |
Other Names | [Parathyroid hormone-like protein PTHrP[107-139] PTHLH PTHRP], [PTHLH; PTHLH; HHM; PLP; BDE2; PTHR; PTHRP; PTHRP; PTH-rP; PTHrP; PLP] |
Gene, Accession # | Gene ID: 5744, NCBI: NP_002811.1, UniProt: P12272 |
Catalog # | MBS1488586 |
Price | $160, $235 |
Order / More Info | Human Parathyroid hormone-related protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |