ESR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityESR1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: ESR1 antibody detects endogenous levels of total ESR1. Description: ER-alpha is a nuclear hormone receptor and transcription factor. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Two splice-variant isoforms have been described.Function: Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 an
ImmunogenImmunogen: Purified recombinant fragment of human ESR1 expressed in E. Coli Subcellular Location: Nucleus. Cytoplasm. Cell Membrane. A minor fraction is associated with the inner membrane and Nucleus. Cytoplasm. Cell Membrane. Associated with the inner membrane via palmitoylation. Tissue Specificity: Widely expressed. Isoform 3 is not expressed in the pituitary gland.
Other Names[DKFZp686N23123; ER alpha; ER; ER-alpha; Era; ESR; ESR1; ESR1_HUMAN; ESRA; Estradiol receptor; Estrogen nuclear receptor alpha; Estrogen receptor 1; Estrogen receptor alpha 3*, 4, 5, 6, 7*/822 isoform; Estrogen receptor alpha; Estrogen receptor alpha delta 3*, 4, 5, 6, 7*, 8*/941 isoform; Estrogen receptor alpha delta 3*, 4, 5, 6, 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*, 5, 6, 7*/654 isoform; Estrogen receptor alpha delta 4*, 5, 6, 7, 8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; ESTRR; NR3A1; Nuclear receptor subfamily 3 group A member 1]
Gene, Accession #[ESR1], Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372
Catalog #MBS9602459
Price$235, $295, $370
Order / More InfoESR1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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