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Antigenic Specificity | p62/SQSTM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulati |
Immunogen | Immunogen: A synthesized peptide derived from human p62/SQSTM1. Sensitivity: p62/SQSTM1 Antibody detects endogenous levels of total p62/SQSTM1 |
Other Names | [OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3; PDB 3; PDB3], [SQSTM1; SQSTM1; p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3; ORCA; OSIL; EBIAP; p60] |
Gene, Accession # | [p62/SQSTM1], Gene ID: 8878, NCBI: NP_001135770.1, UniProt: Q13501 |
Catalog # | MBS477187 |
Price | $335 |
Order / More Info | p62/SQSTM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |