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Antigenic Specificity | ZNF281 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.4 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ZNF281 protein. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Kr??ppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene.Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR. |
Immunogen | Immunogen: Synthetic peptide of human ZNF281 |
Other Names | [ZBP-99; ZNP-99] |
Gene, Accession # | [ZNF281], Gene ID: 23528, NCBI: NP_001268222.1, UniProt: Q9Y2X9 |
Catalog # | MBS9415819 |
Price | $255 |
Order / More Info | ZNF281 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |