LRP5 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-LRP5 antibody, protein, ELISA kits.
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| Antigenic Specificity | LRP5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LRP5 and LRP6 are singlepass transmembrane proteins belonging to the lowdensity lipoprotein receptor (LDLR)related protein family. Unlike other members of the LDLR family, LRP5 and LRP6 have four EGF and three LDLR repeats in the extracellular domain, and prolinerich motifs in the cytoplasmic domain (1). They function as coreceptors for Wnt and are required for the canonical Wnt/betacatenin signaling pathway (2,3). LRP5 and LRP6 are highly homologous and have redundant roles during development (4,5). The activity of LRP5 and LRP6 can be inhibited by the binding of some members of the Dickkopf (DKK) family of proteins (6,7). Upon stimulation with Wnt, LRP6 is phosphorylated at multiple sites including Thr1479, Ser1490, and Thr1493 by kinases |
| Immunogen | Immunogen: A synthetic -peptide of human LRP5 |
| Other Names | [LRP5; LRP5; LRP5; LRP5; BMND1; EVR1; EVR4; HBM; LR3; LRP7; OPPG; OPS; OPTA1; VBCH2;], [LRP5; LRP5; HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; OPTA1; VBCH2; LR3; LRP7; LRP-5] |
| Gene, Accession # | Gene ID: 4041, NCBI: NP_002326.2, UniProt: O75197 |
| Catalog # | MBS126119 |
| Price | $200, $275, $430 |
| Order / More Info | LRP5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Brown, S.D. et al. (1998) Biochem. Biophys. Res. Commun. 248, 879-888. 2. Pinson, K.I. et al. (2000) Nature 407, 535-538. 3. Tamai, K. et al. (2000) Nature 407, 530-535. 4. Kelly, O.G. et al. (2004) Development 131, 2803-2815. 5. He, X. et al. (2004) Development 131, 1663-1677. 6. Semenov, M.V. et al. (2001) Curr Biol 11, 951-61. 7. Bafico, A. et al. (2001) Nat. Cell Biol. 3, 683-668. 8. Tamai, K. et al. (2004) Mol. Cell 13, 149-156. 9. Zeng, X. et al. (2005) Nature 438, 873-877. 10. Davidson, G. et al. (2005) Nature 438, 867-872. 11. Levasseur, R. et al. (2005) Joint Bone Spine 72, 207-14. 12. Ferrari, S.L. et al. (2005) Curr Opin Lipidol 16, 207-14. 13. Balemans, W. and Van Hul, W. (2007) Endocrinology 148, 2622-9. 14. Bjorklund, P. et al. (2007) PLoS Med 4, e328. 15. Bjorklund, P. et al. (2009) PLoS One 4, e4243. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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