P95/NBS1 (Phospho-Ser343) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | P95/NBS1 (Phospho-Ser343) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunoblotting (IB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous human p95/NBS1 only when phosphorylated at serine 343. Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
| Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 343 (S-L-S(p)-Q-G) derived from human p95/NBS1. |
| Other Names | [nibrin isoform 1; Nibrin; nibrin; nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1], [NBN; NBN; ATV; NBS; P95; NBS1; AT-V1; AT-V2; NBS; NBS1; P95] |
| Gene, Accession # | [P95/NBS1], Gene ID: 4683, NCBI: NP_002476.2, UniProt: O60934 |
| Catalog # | MBS191069 |
| Price | $340 |
| Order / More Info | P95/NBS1 (Phospho-Ser343) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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