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Antigenic Specificity | DDR1 (Phospho-Tyr513) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of DDR1 only when phosphorylated at tyrosine 513. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI).di Marco E., J. Biol. Chem. 268:24290-24295 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 513 (K-K-Y(p)-V-R) derived from Human DDR1. |
Other Names | [CAK; RTK6; TRKE; EDDR1] |
Gene, Accession # | [DDR1], Gene ID: 780, NCBI: NP_001189450.1, UniProt: Q08345 |
Catalog # | MBS9406762 |
Price | $200, $255 |
Order / More Info | DDR1 (Phospho-Tyr513) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |