Edit |   |
---|---|
Antigenic Specificity | MAGEA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. |
Immunogen | Immunogen: Recombinant Human Melanoma-associated antigen 3 protein (2-104AA) |
Other Names | [Melanoma-associated antigen 3; Antigen MZ2-D; Cancer/testis antigen 1.3; CT1.3; MAGE-3 antigen; MAGEA3; MAGE3] |
Gene, Accession # | [MAGEA3], Gene ID: 4102, NCBI: NP_005353.1, UniProt: P43357 |
Catalog # | MBS7105718 |
Price | $160, $235 |
Order / More Info | MAGEA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |