PAK4/5/6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPAK4/5/6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: PAK4/5/6 Polyclonal Antibody detects endogenous levels of PAK4/5/6 protein. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK5 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have
ImmunogenImmunogen: Synthesized peptide derived from human PAK4 around the non-phosphorylation site of S474
Other Names[Rabbit PAK4/5/6; PAK4; KIAA1142; Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4]
Gene, Accession #[PAK4/5/6], Gene ID: 10298, NCBI: NP_001014831.1, UniProt: O96013
Catalog #MBS9704103
Price$130, $220, $325
Order / More InfoPAK4/5/6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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