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Antigenic Specificity | CHAF1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). |
Immunogen | Immunogen: Recombinant Human Chromatin assembly factor 1 subunit A protein (840-904AA) |
Other Names | [Chromatin assembly factor 1 subunit A; CAF-1 subunit A; Chromatin assembly factor I p150 subunit; CAF-I 150 kDa subunit; CAF-I p150; hp150; CHAF1A; CAF; CAF1P150] |
Gene, Accession # | [CHAF1A], Gene ID: 10036, NCBI: NP_005474.2, UniProt: Q13111 |
Catalog # | MBS7110115 |
Price | $160, $235 |
Order / More Info | CHAF1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |