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Antigenic Specificity | MAP2K7 (Phospho-Thr275) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MAP2K7 only when phosphorylated at threonine 275. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.Wu Z.,Mol. Cell. Biol. 17:7407-74 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine 275(A-K-T(p)-R-S) derived from Human MAP2K7. |
Other Names | [PRKMK7; JNKK2; MKK7; MAP2K7; MP2K7] |
Gene, Accession # | [MAP2K7], Gene ID: 5609, NCBI: NP_001284484.1, UniProt: O14733 |
Catalog # | MBS9409345 |
Price | $200, $255 |
Order / More Info | MAP2K7 (Phospho-Thr275) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |