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Antigenic Specificity | Mucin 5AC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Mucin-5AC(MUC5AC) detection. Tested with WB, IHC-P in Human. Background: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a direct and critical mediator of resistance during intestinal nematode infection. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Mucin 5AC (552-567aa TMQLFMQLAPKLRGQT). |
Other Names | [Mucin-5AC; mucin 5AC, oligomeric mucus/gel-forming; Apomucin; Gastric mucin; Major Airway Glycoprotein; MUC 5; MUC5; MUC5AC; Mucin 5 subtype AC tracheobronchial; Mucin 5 Subtypes A And C; Mucin 5 subtypes A and C tracheobronchial/gastric; Mucin 5AC oligomeric mucus/gel forming; TBM; Tracheobronchial Mucin], [MUC5AC; MUC5AC; TBM; leB; MUC5; MUC5; MUC-5AC; LeB; TBM] |
Gene, Accession # | [MUC5AC], Gene ID: 4586, NCBI: P98088.3, UniProt: P98088 |
Catalog # | MBS176899 |
Price | $315 |
Order / More Info | Mucin 5AC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |