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Antigenic Specificity | Keratin 17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total keratin 17 protein. May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epit |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human keratin 17. |
Other Names | [Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; K17] |
Gene, Accession # | Gene ID: 3872, NCBI: NP_000413.1, UniProt: Q04695 |
Catalog # | MBS9410165 |
Price | $200, $255 |
Order / More Info | Keratin 17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |