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Antigenic Specificity | STAT5A |
Clone | [1F10F6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | STAT5A, also named as STAT5, belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of STAT5A in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of human STAT5A is found to induce the expression of BCL2L1/BCL-X(L), whi |
Immunogen | Immunogen: Fusion Protein of STAT5A Buffer: PBS with 0.1% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated |
Other Names | [MGF; STAT5; STAT5A] |
Gene, Accession # | [STAT5A], Gene ID: 6776, NCBI: BC027036, UniProt: P42229 |
Catalog # | MBS2549147 |
Price | $220, $290, $435 |
Order / More Info | STAT5A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |