PARP Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PARP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 200 ug/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PARP, a 116 kDa nuclear poly (ADP ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavage targets of caspase 3 in vivo. The cleavage occurs between ASP214 and Gly 215, which separates PARPs N terminal DNA binding domain (24 kDa) from its C terminal catalytic domain (89 kDa). It has been shown that cleavage of PARP facilitates cellular disassembly and inhibition of PARP cleavage attenuates apoptosis in vitro. |
| Immunogen | Immunogen: PARP antibody was raised in Rabbit using synthetic peptide corresponding to caspase cleavage site in human PARP as the immunogen. |
| Other Names | [Rabbit PARP; PARP; PARP; Collagen Type XI Alpha 2; DFNA13; DFNB53; HKE5; STL3; COL11A2] |
| Gene, Accession # | [PARP] |
| Catalog # | MBS5310910 |
| Price | $705 |
| Order / More Info | PARP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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