Edit |   |
---|---|
Antigenic Specificity | PAX4 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PAX4 antibody detects endogenous levels of total PAX4. Description: This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.Function: Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Compete |
Immunogen | Immunogen: Purified recombinant fragment of human PAX4 expressed in E. Coli Subcellular Location: Nucleus. |
Other Names | [KPD; MGC129960; MODY9; Paired box 4; Paired box gene 4; paired box homeotic gene 4; Paired box protein Pax-4; Paired domain gene 4; Pax4; PAX4_HUMAN] |
Gene, Accession # | [PAX4], Gene ID: 5078, NCBI: NP_006184.2, UniProt: O43316 |
Catalog # | MBS9602640 |
Price | $235, $295, $370 |
Order / More Info | PAX4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |