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Antigenic Specificity | RAD50 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using RAD50 antibody. Immunohistochemistry of paraffin-embedded human gastric tissue using RAD50 antibody. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for |
Immunogen | Immunogen: A synthetic peptide of human RAD50 |
Other Names | [Rad50; DNA repair protein RAD50; DNA repair protein RAD50; RAD50 double strand break repair protein] |
Gene, Accession # | [RAD50], Gene ID: 10111, NCBI: AAB07119.1 |
Catalog # | MBS4150237 |
Price | $385 |
Order / More Info | RAD50 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |