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Antigenic Specificity | ASGR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. This gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this |
Immunogen | Immunogen: Rabbit polyclonal ASGR1(1) antibody was raised against a recombinate human ASGR1 protein 96-283aa (BC032130). |
Other Names | [Homo sapiens asialoglycoprotein receptor 1, mRNA; Asialoglycoprotein receptor 1; asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; hepatic lectin H1; asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1], [ASGR1; ASGR1; HL-1; ASGPR; ASGPR1; CLEC4H1] |
Gene, Accession # | [ASGR1], Gene ID: 432, NCBI: BC032130 |
Catalog # | MBS417614 |
Price | $230 |
Order / More Info | ASGR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Onizuka,T., Shimizu,H., Moriwaki,Y., et al. NMR study of ligand release from asialoglycoprotein receptor under solution conditions in early endosomes. FEBS J. 279 (15), 2645-2656 (2012) |