Edit |   |
---|---|
Antigenic Specificity | E2F1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: E2F1 antibody detects endogenous levels of total E2F1. Description: The E2F transcription factors are essential for regulation of the cell cycle (1, 2). Physiological E2F is a heterodimer composed of an E2F subunit together with a DP subunit (3, 4). Six members of the E2F family have been identified, and each E2F subunit has a DNA binding and a dimerization domain. E2F-1 to-5 activate transcription. E2F-1 to-3 bind pRb, and E2F-4 and-5 bind p107 or p130, and these interactions are under cell cycle control (5-8). E2F-1 has oncogenic properties in vivo and in vitro. E2F-1 can induce apoptosis through p53-dependent and-independent mechanisms. E2F-1 is stress-responsive, and is regulated by a PI3-kinase-like kinase family such as t |
Immunogen | Immunogen: A synthetic peptide of human E2F1 Subcellular Location: Nucleus. |
Other Names | [DmelCG6376; Dmel_CG6376; drosE2F1; E(Sev-CycE)3A; E(var)3-93E; E2-promoter binding facto; E2F 1; E2F transcription factor 1; E2F-1; E2f-PA; E2f-PB; E2f-PC; E2F1; E2f1 E2F transcription factor 1; E2F1_HUMAN; Evar(3)164; KIAA4009; l(3)07172; l(3)j3B1; l(3)j3C2; l(3)rM729; mKIAA4009; OTTHUMP00000030661; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1] |
Gene, Accession # | [E2F1], Gene ID: 1869, NCBI: NP_005216.1, UniProt: Q01094 |
Catalog # | MBS9607453 |
Price | $240, $280 |
Order / More Info | E2F1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |