Phospho-CREB (Ser142) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-CREB (Ser142)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-CREB (Ser142) antibody detects endogenous levels of CREB only when phosphorylated at Serine 142. Description: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome.Function: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and th
ImmunogenImmunogen: A synthesized peptide derived from human CREB around the phosphorylation site of Serine 142 Subcellular Location: CREB: Nucleus. CREM: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (91%)
Other Names[Active transcription factor CREB; cAMP response element binding protein 1; cAMP response element binding protein; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; CREB; CREB-1; CREB1; CREB1_HUMAN; Cyclic AMP-responsive element-binding protein 1; MGC9284; OTTHUMP00000163864; OTTHUMP00000163865; OTTHUMP00000206660; OTTHUMP00000206662; OTTHUMP00000206667; Transactivator protein]
Gene, Accession #[CREB], Gene ID: 1385, NCBI: NP_004370.1, UniProt: P16220
Catalog #MBS9600959
Price$240, $280
Order / More InfoPhospho-CREB (Ser142) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesChen J, Zhang C, Mi Y, Chen F, Du D; Journal: Mol Cell Biochem. CREB1 regulates glucose transport of glioma cell line U87 by targeting GLUT1.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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