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Antigenic Specificity | Phospho-CREB (Ser142) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-CREB (Ser142) antibody detects endogenous levels of CREB only when phosphorylated at Serine 142. Description: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome.Function: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and th |
Immunogen | Immunogen: A synthesized peptide derived from human CREB around the phosphorylation site of Serine 142 Subcellular Location: CREB: Nucleus. CREM: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (91%) |
Other Names | [Active transcription factor CREB; cAMP response element binding protein 1; cAMP response element binding protein; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; CREB; CREB-1; CREB1; CREB1_HUMAN; Cyclic AMP-responsive element-binding protein 1; MGC9284; OTTHUMP00000163864; OTTHUMP00000163865; OTTHUMP00000206660; OTTHUMP00000206662; OTTHUMP00000206667; Transactivator protein] |
Gene, Accession # | [CREB], Gene ID: 1385, NCBI: NP_004370.1, UniProt: P16220 |
Catalog # | MBS9600959 |
Price | $240, $280 |
Order / More Info | Phospho-CREB (Ser142) Antibody from MYBIOSOURCE INC. |
Product Specific References | Chen J, Zhang C, Mi Y, Chen F, Du D; Journal: Mol Cell Biochem. CREB1 regulates glucose transport of glioma cell line U87 by targeting GLUT1. |