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Antigenic Specificity | TIM22 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TIM22 antibody detects endogenous levels of TIM22. Function: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).Subunit Structure: Component of the TIM22 complex, whose core is composed of TIMM22, associated with peripheral protein FXC1/TIMM10B and the 70 kDa heterohexamer (PubMed:14726512, PubMed:27265872). In most cases, the 70 kDa complex is composed of TIMM9 and TIMM10 (TIMM10A or TIMM1 |
Immunogen | Immunogen: A synthesized peptide derived from human TIM22. Subcellular Location: Mitochondrion Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (92%), Xenopus (92%) |
Other Names | [Mitochondrial import inner membrane translocase subunit Tim22; Putative membrane protein; Testis expressed sequence 4; TEX 4; TEX4; TIM 22; TIM22; TIMM 22; Translocase of inner mitochondrial membrane 22 homolog] |
Gene, Accession # | [TIM22], Gene ID: 29928, NCBI: NP_037469.2, UniProt: Q9Y584 |
Catalog # | MBS9603464 |
Price | $240, $280 |
Order / More Info | TIM22 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |