RTN4 (N-Term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | RTN4 (N-Term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and a |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Reticulon-4; Foocen; Neurite outgrowth inhibitor; Nogo protein; Neuroendocrine-specific protein; NSP; Neuroendocrine-specific protein C homolog; RTN-x; Reticulon-5; RTN4; KIAA0886; NOGO] |
| Gene, Accession # | [RTN4], Gene ID: 57142, NCBI: NP_008939.1, UniProt: Q9NQC3 |
| Catalog # | MBS9216981 |
| Price | $165, $370 |
| Order / More Info | RTN4 (N-Term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yang J.,et al.Cytogenet. Cell Genet. 88:101-102(2000). Prinjha R.,et al.Nature 403:383-384(2000). Tagami S.,et al.Oncogene 19:5736-5746(2000). Zhou Z.M.,et al.Reproduction 123:227-234(2002). Oertle T.,et al.J. Mol. Biol. 325:299-323(2003). |
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MYBIOSOURCE INC.
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