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Antigenic Specificity | 14-3-3 beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total 14-3-3 b protein. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.Leffers H., J. Mol. Biol. 231:982-998(1993).Deloukas P., Nature 414:865-871(2001).Gevaert K., Nat. Biotechnol. 21:566-569(2003).Chi A., J |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human 14-3-3 b. |
Other Names | [14-3-3 b; 14-3-3 protein beta/alpha; 1433B; 143B; KCIP-1; Protein 1054] |
Gene, Accession # | [14-3-3 beta], Gene ID: 7529, NCBI: NP_003395.1, UniProt: P31946 |
Catalog # | MBS9400990 |
Price | $200, $255 |
Order / More Info | 14-3-3 beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |