14-3-3 beta Antibody from MYBIOSOURCE INC.

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Antigenic Specificity14-3-3 beta
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total 14-3-3 b protein. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.Leffers H., J. Mol. Biol. 231:982-998(1993).Deloukas P., Nature 414:865-871(2001).Gevaert K., Nat. Biotechnol. 21:566-569(2003).Chi A., J
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human 14-3-3 b.
Other Names[14-3-3 b; 14-3-3 protein beta/alpha; 1433B; 143B; KCIP-1; Protein 1054]
Gene, Accession #[14-3-3 beta], Gene ID: 7529, NCBI: NP_003395.1, UniProt: P31946
Catalog #MBS9400990
Price$200, $255
Order / More Info14-3-3 beta Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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