Human CD29 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD29
Clone[12G10]
Host SpeciesMouse
Reactive Specieshuman, mink. does not react with: rat, mouse
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size0.1 mg
Concentration1.0 mg/ml
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionMouse anti Human CD29 monoclonal antibody, clone 12G10 recognizes human CD29 also known as beta1 integrin or VLA-4 subunit alpha. CD29 is a ~130 kDa under reducing, ~115 kDa under non-reducing conditions single pass type I transmembrane glycoprotein. CD29 acts as the common beta subunit of the heterodimeric very late antigens 1-6, complexing with CD49a-f respectively where it forms part of the receptors for laminin, collagen and fibronectin. the VLA heterodimers mediate cell-cell and cell-matrix interactions. Mouse anti Human CD29, clone 12G10 binding to cells adhering via VLA-4 results in actin cytoskeletal disruption and subsequent inhibition of attachment and spreading whilst 12G10 binding to cells adhering via VLA-5 results in enhanceme
ImmunogenImmunogen: Purified human beta1 integrin preparation from HT1080 fibrosarcoma cell extract. Conjugation: FITC
Other Names[CD29 (12G10); Mouse Human CD29], [ITGB1; ITGB1; CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA; FNRB; MDF2; MSK12; GPIIA]
Gene, Accession #[CD29], Gene ID: 3688, NCBI: NP_002202.2, UniProt: P05556
Catalog #MBS225641
Price$370
Order / More InfoHuman CD29 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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