Substance P Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySubstance P
Clone[NC1/34]
Host SpeciesRat
Reactive Specieshuman. predicted: All mammals, Crab, pigeons
IsotypeIgG2a
Formatunconjugated
Size0.5 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionThis antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu-or Met enkephalin, somatostatin or beta-endorphin; crossreactivity with eledoisin: 5%. It recognizes Substance P in post-mortem tissue of the human brain. The discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family; it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotio
ImmunogenImmunogen: Substance P
Other Namesn/a
Gene, Accession #NCBI: ACN37865.1
Catalog #MBS588186
Price$435
Order / More InfoSubstance P Antibody from MYBIOSOURCE INC.
Product Specific References1. Cuello AC-Detection of substance P in the central nervous system by a monoclonal antibody. 2. Cuello AC-Organization of substance P primary sensory neurons: ultrastructural and physiological correlates. 3. Ramien M-Parasympathetic nerve fibers invade the upper dermis following sensory denervation of the rat lower lip skin. 4. Ruocco I-Skin blood vessels are simultaneously innervated by sensory, sympathetic, and parasympathetic fibers.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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