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Antigenic Specificity | BCL-W |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, chicken, bovine, dog |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes Bcl-w protein. It cross-reacts to human, mouse and rat. The other species were not tested. BCL-w is a member of the Bcl-2 family. The gene codes for a 21 kDa protein which is essential for the regulation of cellular survival, and that is up-regulated in different human tumors, such as gastric and colorectal carcinomas. Inhibition of AKT activity may promote apoptosis through the down-regulation of Bcl-w protein and the consequential reduction in interaction of Bcl-w with pro-apoptotic members of the Bcl-2 family. |
Immunogen | Antigen Preparation: A synthetic peptide derived from N-terminus of human BCL-W protein. This sequence is identical among human, rat and mouse origins. |
Other Names | n/a |
Gene, Accession # | [BCL-W] |
Catalog # | MBS462207 |
Price | $285 |
Order / More Info | BCL-W Antibody from MYBIOSOURCE INC. |
Product Specific References | Gibson,L., Bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene 13 (4), 665-675 (1996) |