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Antigenic Specificity | PSMB10 (C-term), 214-242 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.36 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PSMB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human PSMB10. The proteasome is a multicatalytic proteinase complex witha highly ordered ring-shaped 20S core structure. The core structureis composed of 4 rings of 28 non-identical subunits; 2 rings arecomposed of 7 alpha subunits and 2 rings are composed of 7 betasubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene en |
Immunogen | n/a |
Other Names | [Proteasome subunit beta type-10; Low molecular mass protein 10; Macropain subunit MECl-1; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome MECl-1; Proteasome subunit beta-2i; PSMB10; LMP10; MECL1] |
Gene, Accession # | [PSMB10], Gene ID: 5699, NCBI: NP_002792.1, UniProt: P40306 |
Catalog # | MBS9203562 |
Price | $165, $370 |
Order / More Info | PSMB10 (C-term), 214-242 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care (2010) In press : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Moschonas, A., et al. Mol. Cell. Biol. 28(20):6208-6222(2008) Liu, Y., et al. DNA Seq. 18(4):257-264(2007) Listovsky, T., et al. EMBO J. 23(7):1619-1626(2004) |