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Antigenic Specificity | Glut 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Glut 4 pAb detects endogenous levels of total Glut 4 pAb. Description: In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin.Function: Insulin-regulated facilitative glucose transporter.Subunit Structure: Interacts with NDUFA9 (By similarity). Binds to DAXX. Interacts via its N-terminus with SRFBP1.Post-translational Modifications: Sumoylated.Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transpor |
Immunogen | Immunogen: A synthesized peptide derived from human Glut 4 pAb Subcellular Location: Cell Membrane. Endomembrane System. Cytoplasm, Perinuclear Region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration. Tissue Specificity: Skeletal and cardiac muscles; brown and white fat. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit Si |
Other Names | [insulin-responsive; Glucose transporter GLUT 4; Glucose transporter type 4; Glucose transporter type 4 insulin responsive; GLUT 4; GLUT-4; GTR4_HUMAN; Insulin responsive glucose transporter type 4; kug; SLC 2A4; SLC2A4; solute carrier family 2 (facilitated glucose transporter) member 4; Solute carrier family 2 member 4; Solute carrier family 2, facilitated glucose transporter member 4] |
Gene, Accession # | [GLUT4], Gene ID: 6517, NCBI: NP_001033.1, UniProt: P14672 |
Catalog # | MBS9601558 |
Price | $240, $280 |
Order / More Info | Glut 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |