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Antigenic Specificity | HDAC2/Histone Deacetylase 2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetyl |
Immunogen | Immunogen: A synthesized peptide derived from human HDAC2. Subcellular Localization: Nucleus. Cytoplasm. Tissue Specificity: Widely expressed; lower levels in brain and lung. |
Other Names | [Histone deacetylase 2; HD2; 3.5.1.98; HDAC2], [HDAC2; HDAC2; HD2; RPD3; YAF1; HD2] |
Gene, Accession # | [HDAC2], Gene ID: 3066, NCBI: NP_001518.3, UniProt: Q92769 |
Catalog # | MBS179264 |
Price | $160, $340, $340 |
Order / More Info | HDAC2/Histone Deacetylase 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |