HDAC2/Histone Deacetylase 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHDAC2/Histone Deacetylase 2
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsChromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetyl
ImmunogenImmunogen: A synthesized peptide derived from human HDAC2. Subcellular Localization: Nucleus. Cytoplasm. Tissue Specificity: Widely expressed; lower levels in brain and lung.
Other Names[Histone deacetylase 2; HD2; 3.5.1.98; HDAC2], [HDAC2; HDAC2; HD2; RPD3; YAF1; HD2]
Gene, Accession #[HDAC2], Gene ID: 3066, NCBI: NP_001518.3, UniProt: Q92769
Catalog #MBS179264
Price$160, $340, $340
Order / More InfoHDAC2/Histone Deacetylase 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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